Varaico: Literature-Extracted Genetic Variants

Gene:FYB1
Variant:p.V641A

FYB1

46 papers

RefSeq Summary

The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interle...

Pfam Domains

SH3_2aa 515–570UCSCVariant SH3 domain
hSH3aa 695–783UCSCHelically-extended SH3 domain

Gene Aliases

HGNC Name

FYN binding protein 1

HGNC Alias Symbols

SLAP-130; FYB-120/130

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001465.6
p.V641A
c.1922T>C
Surrounding Variants
1 paper
NM_001465.6
p.T647M
c.1940C>T
1 paper
NM_001465.6
p.E668*
c.2002G>T
1 paper
NM_001465.6
p.V672F
c.2014G>T
1 paper
NM_001465.6
p.E630K
c.1888G>A
1 paper
NM_199335.5
p.Y651F
c.1952A>T
1 paper
NM_001465.6
p.E600Q
c.1798G>C
1 paper
NM_001465.6
p.Y595F
c.1784A>T
2 papers
NM_001465.6
p.Y571F
c.1712A>T
1 paper
NM_001465.6
p.Y559F
c.1676A>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."