Varaico: Literature-Extracted Genetic Variants

Gene:FYB1
Variant:p.G324insFs

FYB1

46 papers

RefSeq Summary

The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interle...

Pfam Domains

SH3_2aa 515–570UCSCVariant SH3 domain
hSH3aa 695–783UCSCHelically-extended SH3 domain

Gene Aliases

HGNC Name

FYN binding protein 1

HGNC Alias Symbols

SLAP-130; FYB-120/130

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001465.6
p.G324insFs
c.971dupG
Surrounding Variants
1 paper
NM_001465.6
p.P325fs
c.973_974fs
1 paper
NM_001465.6
p.K332R
c.995A>G
1 paper
NM_001465.6
p.G335E
c.1004G>A
1 paper
NM_001465.6
p.K334insFs
c.1002dupG
1 paper
NM_001465.6
p.Q344H
c.1032G>T
1 paper
NM_001465.6
p.K287M
c.860A>T
1 paper
NM_001465.6
p.K283insFs
c.848dupA
1 paper
NM_001465.6
p.D367G
c.1100A>G
1 paper
NM_001465.6
p.D244G
c.731A>G
1 paper
NM_001465.6
p.M216I
c.648G>A
1 paper
NM_001465.6
p.P202L
c.605C>T
3 papers
NM_001465.6
p.W131*
c.393G>A
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