Varaico: Literature-Extracted Genetic Variants

Gene:FYB1
Variant:p.T11K

FYB1

46 papers

RefSeq Summary

The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interle...

Pfam Domains

SH3_2aa 515–570UCSCVariant SH3 domain
hSH3aa 695–783UCSCHelically-extended SH3 domain

Gene Aliases

HGNC Name

FYN binding protein 1

HGNC Alias Symbols

SLAP-130; FYB-120/130

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001465.6
p.T11K
c.32C>A
Surrounding Variants
1 paper
NM_001465.6
p.T6M
c.17C>T
1 paper
NM_001465.6
p.K36N
c.108G>T
1 paper
NM_001465.6
p.K36N
c.108G>C
1 paper
NM_001465.6
p.P47R
c.140C>G
1 paper
NM_001465.6
p.P81L
c.242C>T
2 papers
NM_001465.6
p.W131*
c.392G>A
3 papers
NM_001465.6
p.W131*
c.393G>A
1 paper
NM_001465.6
p.P202L
c.605C>T
1 paper
NM_001465.6
p.M216I
c.648G>A
1 paper
NM_001465.6
p.D244G
c.731A>G
1 paper
NM_001465.6
p.K283insFs
c.848dupA
1 paper
NM_001465.6
p.K287M
c.860A>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."