Varaico: Literature-Extracted Genetic Variants

FYN

269 papers

RefSeq Summary

This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates wi...

Pfam Domains

SH3_1aa 88–135UCSCSH3 domain

SH2aa 149–231UCSCSH2 domain

PK_Tyr_Ser-Thraa 271–520UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FYN proto-oncogene, Src family tyrosine kinase

HGNC Alias Symbol

MGC45350

Papers

RefSeq ID

Protein change

DNA change

1–12 of 158 variants

6 papers

NM_002037.5

p.R176C

c.526C>T

5 papers

NM_002037.5

p.R96W

c.286C>T

5 papers

NM_002037.5

p.K505delFs

c.1514delT

5 papers

NM_002037.5

p.Y531H

c.1591T>C

4 papers

NM_002037.5

p.L174R

c.521T>G

4 papers

NM_002037.5

p.G410R

c.1228G>A

3 papers

NM_002037.5

p.R206C

c.616C>T

3 papers

NM_002037.5

p.G410R

c.1228G>C

3 papers

NM_002037.5

p.Y531F

c.1592A>T

2 papers

NM_002037.5

p.R96G

c.286C>G

2 papers

NM_002037.5

p.R96L

c.287G>T

2 papers

NM_002037.5

p.E107Q

c.319G>C