Varaico: Literature-Extracted Genetic Variants

FYN

269 papers

RefSeq Summary

This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates wi...

Pfam Domains

SH3_1aa 88–135UCSCSH3 domain

SH2aa 149–231UCSCSH2 domain

PK_Tyr_Ser-Thraa 271–520UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FYN proto-oncogene, Src family tyrosine kinase

HGNC Alias Symbol

MGC45350

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002037.5

p.D506E

c.1518C>G

Surrounding Variants

2 papers

NM_002037.5

p.D506E

c.1518C>A

1 paper

NM_002037.5

p.P507L

c.1520C>T

5 papers

NM_002037.5

p.K505delFs

c.1514delT

2 papers

NM_002037.5

p.K505fs

c.1513_1514fs

1 paper

NM_002037.5

p.H501Y

c.1501C>T

1 paper

NM_002037.5

p.Y515C

c.1544A>G

1 paper

NM_002037.5

p.Q517E

c.1549C>G

1 paper

NM_002037.5

p.Q489R

c.1466A>G

1 paper

NM_002037.5

p.P488L

c.1463C>T

1 paper

NM_002037.5

p.A526V

c.1577C>T

1 paper

NM_002037.5

p.E528G

c.1583A>G

5 papers

NM_002037.5

p.Y531H

c.1591T>C