Varaico: Literature-Extracted Genetic Variants

FYN

269 papers

RefSeq Summary

This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates wi...

Pfam Domains

SH3_1aa 88–135UCSCSH3 domain

SH2aa 149–231UCSCSH2 domain

PK_Tyr_Ser-Thraa 271–520UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

FYN proto-oncogene, Src family tyrosine kinase

HGNC Alias Symbol

MGC45350

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002037.5

p.R392R

c.1176A>T

Surrounding Variants

1 paper

NM_002037.5

p.V398L

c.1192G>T

1 paper

NM_002037.5

p.V398L

c.1192G>C

1 paper

NM_002037.5

p.Y386F

c.1157A>T

1 paper

NM_002037.5

p.R383C

c.1147C>T

1 paper

NM_002037.5

p.A376G

c.1127C>G

1 paper

NM_002037.5

p.A376T

c.1126G>A

3 papers

NM_002037.5

p.G410R

c.1228G>C

4 papers

NM_002037.5

p.G410R

c.1228G>A

1 paper

NM_002037.5

p.Q373_V374Splc

c.1120-1G>C

1 paper

NM_002037.5

p.R413Q

c.1238G>A

1 paper

NM_002037.5

p.Y420F

c.1259A>T

1 paper

NM_002037.5

p.E358_G359insFs

c.1074_1075insC