Varaico: Literature-Extracted Genetic Variants

Gene:FZD4
Variant:p.L486W

FZD4

267 papers

RefSeq Summary

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling ...

Pfam Domains

Fzaa 45–152UCSCFz domain
Frizzledaa 210–511UCSCFrizzled/Smoothened family membrane region

Gene Aliases

HGNC Name

frizzled class receptor 4

HGNC Previous Symbol

EVR1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_012193.4
p.L486W
c.1457T>G
Surrounding Variants
1 paper
NM_012193.4
p.L486F
c.1458G>T
1 paper
NM_012193.4
p.L486F
c.1458G>C
1 paper
NM_012193.4
p.L485F
c.1455G>T
1 paper
NM_012193.4
p.L485F
c.1455G>C
5 papers
NM_012193.4
p.G488V
c.1463G>T
20 papers
NM_012193.4
p.G488D
c.1463G>A
1 paper
NM_012193.4
p.I481S
c.1442T>G
1 paper
NM_012193.4
p.I481T
c.1442T>C
2 papers
NM_012193.4
p.S491*
c.1472C>G
2 papers
NM_012193.4
p.S491*
c.1472C>A
2 papers
NM_012193.4
p.I481L
c.1441A>C
5 papers
NM_012193.4
p.G492R
c.1474G>C
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