Varaico: Literature-Extracted Genetic Variants

GABBR2

156 papers

RefSeq Summary

The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-...

Pfam Domains

ANF_receptoraa 76–434UCSCReceptor family ligand binding region

7tm_3aa 475–743UCSC7 transmembrane sweet-taste receptor of 3 GCPR

GBR2_CCaa 779–817UCSCGamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain

Gene Aliases

HGNC Name

gamma-aminobutyric acid type B receptor subunit 2

HGNC Previous Symbol

GPR51

Papers

RefSeq ID

Protein change

DNA change

1–12 of 165 variants

27 papers

NM_005458.8

p.A567T

c.1699G>A

10 papers

NM_005458.8

p.S695I

c.2084G>T

9 papers

NM_005458.8

p.I705N

c.2114T>A

8 papers

NM_005458.8

p.G693W

c.2077G>T

7 papers

NM_005458.8

p.A707T

c.2119G>A

5 papers

NM_005458.8

p.R212Q

c.635G>A

4 papers

NM_005458.8

p.T394M

c.1181C>T

4 papers

NM_005458.8

p.G440R

c.1318G>C

4 papers

NM_005458.8

p.G440R

c.1318G>A

3 papers

NM_005458.8

p.V138I

c.412G>A

3 papers

NM_005458.8

p.P282L

c.845C>T

3 papers

NM_005458.8

p.M668L

c.2002A>T