Varaico: Literature-Extracted Genetic Variants

GABBR2

156 papers

RefSeq Summary

The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-...

Pfam Domains

ANF_receptoraa 76–434UCSCReceptor family ligand binding region

7tm_3aa 475–743UCSC7 transmembrane sweet-taste receptor of 3 GCPR

GBR2_CCaa 779–817UCSCGamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain

Gene Aliases

HGNC Name

gamma-aminobutyric acid type B receptor subunit 2

HGNC Previous Symbol

GPR51

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005458.8

p.I704N

c.2111T>A

Surrounding Variants

1 paper

NM_005458.8

p.C703C

c.2109C>T

9 papers

NM_005458.8

p.I705N

c.2114T>A

1 paper

NM_005458.8

p.M702I

c.2106G>T

1 paper

NM_005458.8

p.G706R

c.2116G>C

1 paper

NM_005458.8

p.M702I

c.2106G>C

1 paper

NM_005458.8

p.G706R

c.2116G>A

1 paper

NM_005458.8

p.M702I

c.2106G>A

2 papers

NM_005458.8

p.M702V

c.2104A>G

7 papers

NM_005458.8

p.A707T

c.2119G>A

1 paper

NM_005458.8

p.A707A

c.2121C>T

1 paper

NM_005458.8

p.A707_A708ins3

c.2121_2122ins9

10 papers

NM_005458.8

p.S695I

c.2084G>T