Varaico: Literature-Extracted Genetic Variants

GABBR2

156 papers

RefSeq Summary

The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-...

Pfam Domains

ANF_receptoraa 76–434UCSCReceptor family ligand binding region

7tm_3aa 475–743UCSC7 transmembrane sweet-taste receptor of 3 GCPR

GBR2_CCaa 779–817UCSCGamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain

Gene Aliases

HGNC Name

gamma-aminobutyric acid type B receptor subunit 2

HGNC Previous Symbol

GPR51

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005458.8

p.S695N

c.2084G>A

Surrounding Variants

10 papers

NM_005458.8

p.S695I

c.2084G>T

1 paper

NM_005458.8

p.M694T

c.2081T>C

8 papers

NM_005458.8

p.G693W

c.2077G>T

1 paper

NM_005458.8

p.I692I

c.2076C>T

1 paper

NM_005458.8

p.I692V

c.2074A>G

1 paper

NM_005458.8

p.Y691C

c.2072A>G

1 paper

NM_005458.8

p.Y691S

c.2072A>C

1 paper

NM_005458.8

p.K690R

c.2069A>G

2 papers

NM_005458.8

p.M702V

c.2104A>G

1 paper

NM_005458.8

p.M702I

c.2106G>T

1 paper

NM_005458.8

p.M702I

c.2106G>C

1 paper

NM_005458.8

p.M702I

c.2106G>A