Varaico: Literature-Extracted Genetic Variants

GAS6

114 papers

RefSeq Summary

This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has b...

Pfam Domains

Glaaa 53–93UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

cEGFaa 177–200UCSCComplement Clr-like EGF-like

hEGFaa 207–227UCSCHuman growth factor-like EGF

EGF_CAaa 238–277UCSCCalcium-binding EGF domain

Laminin_G_1aa 325–454UCSCLaminin G domain

Laminin_G_2aa 513–651UCSCLaminin G domain

Gene Aliases

HGNC Name

growth arrest specific 6

HGNC Previous Symbol

AXLLG

Papers

RefSeq ID

Protein change

DNA change

1–12 of 114 variants

19 papers

NM_000820.4

p.E278_D279Splc

c.834+7G>A

6 papers

NM_000820.4

p.C444C

c.1332C>T

3 papers

NM_000820.4

p.L421L

c.1263G>C

2 papers

NM_000820.4

p.D94Splc

c.280+170C>G

2 papers

NM_000820.4

p.G150delFs

c.449delC

2 papers

NM_000820.4

p.A210V

c.629C>T

2 papers

NM_000820.4

p.E241K

c.721G>A

2 papers

NM_000820.4

p.T259P

c.775A>C

2 papers

NM_000820.4

p.V288M

c.862G>A

2 papers

NM_000820.4

p.A623A

c.1869T>C

2 papers

NM_000820.4

p.P672delFs

c.2016delG

1 paper

NM_000820.4

p.P3L

c.8C>T