Varaico: Literature-Extracted Genetic Variants

GAS6

114 papers

RefSeq Summary

This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has b...

Pfam Domains

Glaaa 53–93UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

cEGFaa 177–200UCSCComplement Clr-like EGF-like

hEGFaa 207–227UCSCHuman growth factor-like EGF

EGF_CAaa 238–277UCSCCalcium-binding EGF domain

Laminin_G_1aa 325–454UCSCLaminin G domain

Laminin_G_2aa 513–651UCSCLaminin G domain

Gene Aliases

HGNC Name

growth arrest specific 6

HGNC Previous Symbol

AXLLG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000820.4

p.P672T

c.2014C>A

Surrounding Variants

1 paper

NM_000820.4

p.P672A

c.2014C>G

1 paper

NM_000820.4

p.P671L

c.2012C>T

1 paper

NM_000820.4

p.P672insFs

c.2016dupC

1 paper

NM_000820.4

p.V673fs

c.2017_2018fs

2 papers

NM_000820.4

p.P672delFs

c.2016delG

1 paper

NM_000820.4

p.C670Y

c.2009G>A

1 paper

NM_000820.4

p.T666M

c.1997C>T

1 paper

NM_000820.4

p.D664N

c.1990G>A

1 paper

NM_000820.4

p.G642D

c.1925G>A

1 paper

NM_000820.4

p.R641H

c.1922G>A

1 paper

NM_000820.4

p.D628Splc

c.1882+383C>G

1 paper

NM_000820.4

p.L626delFs

c.1877delA