Varaico: Literature-Extracted Genetic Variants

GAS6

114 papers

RefSeq Summary

This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has b...

Pfam Domains

Glaaa 53–93UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

cEGFaa 177–200UCSCComplement Clr-like EGF-like

hEGFaa 207–227UCSCHuman growth factor-like EGF

EGF_CAaa 238–277UCSCCalcium-binding EGF domain

Laminin_G_1aa 325–454UCSCLaminin G domain

Laminin_G_2aa 513–651UCSCLaminin G domain

Gene Aliases

HGNC Name

growth arrest specific 6

HGNC Previous Symbol

AXLLG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000820.4

p.D541V

c.1622A>T

Surrounding Variants

1 paper

NM_000820.4

p.T545T

c.1635G>T

1 paper

NM_000820.4

p.T545T

c.1635G>C

1 paper

NM_000820.4

p.K546N

c.1638G>T

1 paper

NM_000820.4

p.K546N

c.1638G>C

1 paper

NM_000820.4

p.R531H

c.1592G>A

1 paper

NM_000820.4

p.Q551Q

c.1653G>A

1 paper

NM_000820.4

p.A511S

c.1531G>T

1 paper

NM_000820.4

p.G500R

c.1498G>A

1 paper

NM_000820.4

p.R494Q

c.1481G>A

1 paper

NM_000820.4

p.M493Splc

c.1478-94C>G

1 paper

NM_000820.4

p.A556V

c.1667C>T

1 paper

NM_000820.4

p.G572S

c.1714G>A