Varaico: Literature-Extracted Genetic Variants

GAS6

114 papers

RefSeq Summary

This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has b...

Pfam Domains

Glaaa 53–93UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

cEGFaa 177–200UCSCComplement Clr-like EGF-like

hEGFaa 207–227UCSCHuman growth factor-like EGF

EGF_CAaa 238–277UCSCCalcium-binding EGF domain

Laminin_G_1aa 325–454UCSCLaminin G domain

Laminin_G_2aa 513–651UCSCLaminin G domain

Gene Aliases

HGNC Name

growth arrest specific 6

HGNC Previous Symbol

AXLLG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000820.4

p.M378K

c.1133T>A

Surrounding Variants

1 paper

NM_000820.4

p.W379L

c.1136G>T

1 paper

NM_000820.4

p.W345C

c.1035G>T

1 paper

NM_000820.4

p.E331D

c.993G>T

1 paper

NM_000820.4

p.E331D

c.993G>C

1 paper

NM_000820.4

p.E331K

c.991G>A

1 paper

NM_000820.4

p.R310H

c.929G>A

1 paper

NM_000820.4

p.R310S

c.928C>A

1 paper

NM_000820.4

p.R308*

c.922C>T

1 paper

NM_000820.4

p.F301S

c.902T>C

1 paper

NM_000820.4

p.G298D

c.893G>A

2 papers

NM_000820.4

p.V288M

c.862G>A

19 papers

NM_000820.4

p.E278_D279Splc

c.834+7G>A