Varaico: Literature-Extracted Genetic Variants

GAS6

114 papers

RefSeq Summary

This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has b...

Pfam Domains

Glaaa 53–93UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

cEGFaa 177–200UCSCComplement Clr-like EGF-like

hEGFaa 207–227UCSCHuman growth factor-like EGF

EGF_CAaa 238–277UCSCCalcium-binding EGF domain

Laminin_G_1aa 325–454UCSCLaminin G domain

Laminin_G_2aa 513–651UCSCLaminin G domain

Gene Aliases

HGNC Name

growth arrest specific 6

HGNC Previous Symbol

AXLLG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000820.4

p.C223S

c.667T>A

Surrounding Variants

1 paper

NM_000820.4

p.C223S

c.668G>C

1 paper

NM_000820.4

p.E225K

c.673G>A

1 paper

NM_000820.4

p.Y219S

c.656A>C

2 papers

NM_000820.4

p.A210V

c.629C>T

1 paper

NM_000820.4

p.A206V

c.617C>T

1 paper

NM_000820.4

p.D238Splc

c.712+26G>A

1 paper

NM_000820.4

p.D197Splc

c.590-3C>T

1 paper

NM_000820.4

p.D197Splc

c.590-50C>T

1 paper

NM_000820.4

p.D238Splc

c.713-155T>C

2 papers

NM_000820.4

p.E241K

c.721G>A

1 paper

NM_000820.4

p.R246C

c.736C>T

1 paper

NM_000820.4

p.R246H

c.737G>A