Varaico: Literature-Extracted Genetic Variants

GAS6

114 papers

RefSeq Summary

This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has b...

Pfam Domains

Glaaa 53–93UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

cEGFaa 177–200UCSCComplement Clr-like EGF-like

hEGFaa 207–227UCSCHuman growth factor-like EGF

EGF_CAaa 238–277UCSCCalcium-binding EGF domain

Laminin_G_1aa 325–454UCSCLaminin G domain

Laminin_G_2aa 513–651UCSCLaminin G domain

Gene Aliases

HGNC Name

growth arrest specific 6

HGNC Previous Symbol

AXLLG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000820.4

p.T111N

c.332C>A

Surrounding Variants

1 paper

NM_000820.4

p.G108V

c.323G>T

1 paper

NM_000820.4

p.S107L

c.320C>T

2 papers

NM_000820.4

p.D94Splc

c.280+170C>G

1 paper

NM_000820.4

p.L93V

c.277T>G

1 paper

NM_000820.4

p.T85_D86Splc

c.256-153C>T

1 paper

NM_000820.4

p.T130A

c.388A>G

1 paper

NM_000820.4

p.G138C

c.412G>T

1 paper

NM_000820.4

p.F141C

c.422T>G

1 paper

NM_000820.4

p.W148*

c.443G>A

1 paper

NM_000820.4

p.W148C

c.444G>C

1 paper

NM_000820.4

p.W148*

c.444G>A

1 paper

NM_000820.4

p.G150fs

c.448_449fs