Varaico: Literature-Extracted Genetic Variants

GAS6

114 papers

RefSeq Summary

This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has b...

Pfam Domains

Glaaa 53–93UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

cEGFaa 177–200UCSCComplement Clr-like EGF-like

hEGFaa 207–227UCSCHuman growth factor-like EGF

EGF_CAaa 238–277UCSCCalcium-binding EGF domain

Laminin_G_1aa 325–454UCSCLaminin G domain

Laminin_G_2aa 513–651UCSCLaminin G domain

Gene Aliases

HGNC Name

growth arrest specific 6

HGNC Previous Symbol

AXLLG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000820.4

p.P3L

c.8C>T

Surrounding Variants

1 paper

NM_000820.4

p.S4S

c.12G>C

1 paper

NM_000820.4

p.P34L

c.101C>T

1 paper

NM_000820.4

p.E37Q

c.109G>C

1 paper

NM_000820.4

p.E37G

c.110A>G

1 paper

NM_000820.4

p.F41F

c.123C>T

1 paper

NM_000820.4

p.Q46H

c.138G>C

1 paper

NM_000820.4

p.F53S

c.158T>C

1 paper

NM_000820.4

p.E55D

c.165G>T

1 paper

NM_000820.4

p.E55D

c.165G>C

1 paper

NM_000820.4

p.V66M

c.196G>A

1 paper

NM_000820.4

p.E67K

c.199G>A

1 paper

NM_000820.4

p.S71I

c.212G>T