Varaico: Literature-Extracted Genetic Variants

Gene:GCG
Variant:p.A115S

GCG

1,183 papers

RefSeq Summary

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering a...

Pfam Domains

Hormone_2aa 52–80UCSCPeptide hormone
Hormone_2aa 97–125UCSCPeptide hormone
Hormone_2aa 145–173UCSCPeptide hormone

Gene Aliases

HGNC Name

glucagon

HGNC Alias Symbols

GLP1; GLP2; GRPP; GLP-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002054.5
p.A115S
c.343G>T
Surrounding Variants
2 papers
NM_002054.5
p.A115V
c.344C>T
1 paper
NM_002054.5
p.A115G
c.344C>G
1 paper
NM_002054.5
p.A115A
c.345T>A
1 paper
NM_002054.5
p.Q114P
c.341A>C
1 paper
NM_002054.5
p.A116P
c.346G>C
1 paper
NM_002054.5
p.A116T
c.346G>A
2 papers
NM_002054.5
p.Q114*
c.340C>T
1 paper
NM_002054.5
p.G113G
c.339C>T
1 paper
NM_002054.5
p.A116G
c.347C>G
1 paper
NM_002054.5
p.G113_A115del3
c.337_344del9
1 paper
NM_002054.5
p.G113D
c.338G>A
1 paper
NM_002054.5
p.A116A
c.348C>G
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