Varaico: Literature-Extracted Genetic Variants

Gene:GCG
Variant:p.F58L

GCG

1,183 papers

RefSeq Summary

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering a...

Pfam Domains

Hormone_2aa 52–80UCSCPeptide hormone
Hormone_2aa 97–125UCSCPeptide hormone
Hormone_2aa 145–173UCSCPeptide hormone

Gene Aliases

HGNC Name

glucagon

HGNC Alias Symbols

GLP1; GLP2; GRPP; GLP-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002054.5
p.F58L
c.172T>C
Surrounding Variants
2 papers
NM_002054.5
p.F58Y
c.173T>A
1 paper
NM_002054.5
p.T57I
c.170C>T
1 paper
NM_002054.5
p.F58L
c.174C>G
2 papers
NM_002054.5
p.F58L
c.174C>A
1 paper
NM_002054.5
p.F58delFs
c.173delA
3 papers
NM_002054.5
p.T59S
c.175A>T
1 paper
NM_002054.5
p.T57S
c.169A>T
5 papers
NM_002054.5
p.T59A
c.175A>G
1 paper
NM_002054.5
p.T59P
c.175A>C
1 paper
NM_002054.5
p.F58insFs
c.174dupC
1 paper
NM_002054.5
p.T59S
c.176C>G
1 paper
NM_002054.5
p.G56insFs
c.167_168insC
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