Varaico: Literature-Extracted Genetic Variants

Gene:GCG
Variant:p.F11L

GCG

1,183 papers

RefSeq Summary

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering a...

Pfam Domains

Hormone_2aa 52–80UCSCPeptide hormone
Hormone_2aa 97–125UCSCPeptide hormone
Hormone_2aa 145–173UCSCPeptide hormone

Gene Aliases

HGNC Name

glucagon

HGNC Alias Symbols

GLP1; GLP2; GRPP; GLP-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_002054.5
p.F11L
c.33T>A
Surrounding Variants
1 paper
NM_002054.5
p.F11C
c.32T>G
1 paper
NM_002054.5
p.V12L
c.34G>T
1 paper
NM_002054.5
p.F11insFs
c.31_32insT
1 paper
NM_002054.5
p.F11V
c.31T>G
2 papers
NM_002054.5
p.V12E
c.35T>A
1 paper
NM_002054.5
p.F11I
c.31T>A
2 papers
NM_002054.5
p.L10F
c.30A>T
1 paper
NM_002054.5
p.V12V
c.36A>T
1 paper
NM_002054.5
p.L10L
c.30A>G
3 papers
NM_002054.5
p.L10F
c.30A>C
1 paper
NM_002054.5
p.L10*
c.29T>G
1 paper
NM_002054.5
p.L10S
c.29T>C
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