Varaico: Literature-Extracted Genetic Variants

Gene:GCGR
Variant:p.Y233*

GCGR

217 papers

RefSeq Summary

The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[prov...

Pfam Domains

HRMaa 55–124UCSCHormone receptor domain
7tm_2aa 138–396UCSC7 transmembrane receptor (Secretin family)

Gene Aliases

HGNC Name

glucagon receptor

HGNC Alias Symbol

GGR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000160.5
p.Y233*
c.699T>A
Surrounding Variants
1 paper
NM_000160.5
p.V236M
c.706G>A
1 paper
NM_000160.5
p.M231V
c.691A>G
1 paper
NM_000160.5
p.V229G
c.686T>G
1 paper
NM_000160.5
p.V229L
c.685G>C
1 paper
NM_000160.5
p.V229L
c.685G>T
1 paper
NM_000160.5
p.A228V
c.683C>T
1 paper
NM_000160.5
p.Y239C
c.716A>G
1 paper
NM_000160.5
p.A228T
c.682G>A
1 paper
NM_000160.5
p.C240S
c.718T>A
1 paper
NM_000160.5
p.C240S
c.719G>C
1 paper
NM_000160.5
p.C240F
c.719G>T
11 papers
NM_000160.5
p.R225H
c.674G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."