Varaico: Literature-Extracted Genetic Variants

Gene:GCGR
Variant:p.A366S

GCGR

217 papers

RefSeq Summary

The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[prov...

Pfam Domains

HRMaa 55–124UCSCHormone receptor domain
7tm_2aa 138–396UCSC7 transmembrane receptor (Secretin family)

Gene Aliases

HGNC Name

glucagon receptor

HGNC Alias Symbol

GGR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000160.5
p.A366S
c.1096G>T
Surrounding Variants
1 paper
NM_000160.5
p.F365F
c.1095C>T
11 papers
NM_000160.5
p.V368M
c.1102G>A
1 paper
NM_000160.5
p.V368L
c.1102G>C
1 paper
NM_000160.5
p.V368L
c.1102G>T
1 paper
NM_000160.5
p.T369M
c.1106C>T
1 paper
NM_000160.5
p.E362K
c.1084G>A
1 paper
NM_000160.5
p.E362Q
c.1084G>C
1 paper
NM_000160.5
p.E362*
c.1084G>T
1 paper
NM_000160.5
p.D370A
c.1109A>C
2 papers
NM_000160.5
p.R378C
c.1132C>T
1 paper
NM_000160.5
p.T353I
c.1058C>T
1 paper
NM_000160.5
p.T353A
c.1057A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."