Varaico: Literature-Extracted Genetic Variants

Gene:GJA8
Variant:p.G94R

GJA8

505 papers

RefSeq Summary

This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a ...

Pfam Domains

Connexinaa 3–229UCSCConnexin
Connexin50aa 260–326UCSCGap junction alpha-8 protein (Cx50)

Gene Aliases

HGNC Name

gap junction protein alpha 8

HGNC Previous Symbols

CAE1; CZP1; CAE

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
10 papers
NM_005267.5
p.G94R
c.280G>C
Surrounding Variants
10 papers
NM_005267.5
p.G94R
c.280G>A
8 papers
NM_005267.5
p.G94E
c.281G>A
1 paper
NM_005267.5
p.V93_G94del1
c.279_281delGGG
1 paper
NM_005267.5
p.V93M
c.277G>A
1 paper
NM_005267.5
p.V93L
c.277G>C
1 paper
NM_005267.5
p.V93L
c.277G>T
3 papers
NM_005267.5
p.H95R
c.284A>G
1 paper
NM_005267.5
p.Y92Y
c.276C>T
1 paper
NM_005267.5
p.H95H
c.285C>T
1 paper
NM_005267.5
p.A96P
c.286G>C
1 paper
NM_005267.5
p.A96S
c.286G>T
1 paper
NM_005267.5
p.A96V
c.287C>T
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