Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000170.3

p.I818S

c.2453T>G

Surrounding Variants

1 paper

NM_000170.3

p.I818T

c.2453T>C

1 paper

NM_000170.3

p.I818N

c.2453T>A

1 paper

NM_000170.3

p.I818F

c.2452A>T

2 papers

NM_000170.3

p.K819E

c.2455A>G

3 papers

NM_000170.3

p.Y817C

c.2450A>G

3 papers

NM_000170.3

p.K819_M820Splc

c.2457+2T>A

2 papers

NM_000170.3

p.A816T

c.2446G>A

3 papers

NM_000170.3

p.S814F

c.2441C>T

1 paper

NM_000170.3

p.S814C

c.2441C>G

1 paper

NM_000170.3

p.S814Y

c.2441C>A

1 paper

NM_000170.3

p.S814P

c.2440T>C

1 paper

NM_000170.3

p.I813F

c.2437A>T