Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

26 papers

NM_000170.3

p.A802V

c.2405C>T

Surrounding Variants

3 papers

NM_000170.3

p.A802E

c.2405C>A

1 paper

NM_000170.3

p.A802A

c.2406G>A

1 paper

NM_000170.3

p.S801I

c.2402G>T

1 paper

NM_000170.3

p.S801N

c.2402G>A

2 papers

NM_000170.3

p.A803V

c.2408C>T

1 paper

NM_000170.3

p.V800I

c.2398G>A

2 papers

NM_000170.3

p.W805*

c.2414G>A

1 paper

NM_000170.3

p.T799S

c.2396C>G

2 papers

NM_000170.3

p.W805*

c.2415G>A

1 paper

NM_000170.3

p.T799S

c.2395A>T

3 papers

NM_000170.3

p.G806R

c.2416G>C

1 paper

NM_000170.3

p.S807Y

c.2420C>A