Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000170.3

p.G771V

c.2312G>T

Surrounding Variants

8 papers

NM_000170.3

p.G771R

c.2311G>C

8 papers

NM_000170.3

p.G771R

c.2311G>A

2 papers

NM_000170.3

p.V772Splc

c.2315+2T>G

3 papers

NM_000170.3

p.P769L

c.2306C>T

2 papers

NM_000170.3

p.P769T

c.2305C>A

1 paper

NM_000170.3

p.G768V

c.2303G>T

3 papers

NM_000170.3

p.G768E

c.2303G>A

1 paper

NM_000170.3

p.G768R

c.2302G>C

1 paper

NM_000170.3

p.G768R

c.2302G>A

1 paper

NM_000170.3

p.M767V

c.2299A>G

2 papers

NM_000170.3

p.G766V

c.2297G>T

4 papers

NM_000170.3

p.G766C

c.2296G>T