Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000170.3

p.P765T

c.2293C>A

Surrounding Variants

3 papers

NM_000170.3

p.P765S

c.2293C>T

1 paper

NM_000170.3

p.P765A

c.2293C>G

4 papers

NM_000170.3

p.G766C

c.2296G>T

1 paper

NM_000170.3

p.G766R

c.2296G>C

1 paper

NM_000170.3

p.G763G

c.2289T>G

2 papers

NM_000170.3

p.G766V

c.2297G>T

2 papers

NM_000170.3

p.G763D

c.2288G>A

2 papers

NM_000170.3

p.G763R

c.2287G>C

1 paper

NM_000170.3

p.M767V

c.2299A>G

1 paper

NM_000170.3

p.G762V

c.2285G>T

1 paper

NM_000170.3

p.G762A

c.2285G>C

1 paper

NM_000170.3

p.G762E

c.2285G>A