Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000170.3

p.K754R

c.2261A>G

Surrounding Variants

1 paper

NM_000170.3

p.K754M

c.2261A>T

1 paper

NM_000170.3

p.K754T

c.2261A>C

4 papers

NM_000170.3

p.H753P

c.2258A>C

1 paper

NM_000170.3

p.L752R

c.2255T>G

1 paper

NM_000170.3

p.L752H

c.2255T>A

4 papers

NM_000170.3

p.F756del1

c.2266_2267delGAA

1 paper

NM_000170.3

p.P759S

c.2275C>T

2 papers

NM_000170.3

p.P759R

c.2276C>G

1 paper

NM_000170.3

p.S748W

c.2243C>G

2 papers

NM_000170.3

p.H760R

c.2279A>G

2 papers

NM_000170.3

p.H760P

c.2279A>C

1 paper

NM_000170.3

p.S748A

c.2242T>G