Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000170.3

p.D746E

c.2238T>A

Surrounding Variants

2 papers

NM_000170.3

p.D746E

c.2238T>G

1 paper

NM_000170.3

p.V747F

c.2239G>T

1 paper

NM_000170.3

p.V747L

c.2239G>C

1 paper

NM_000170.3

p.V747I

c.2239G>A

1 paper

NM_000170.3

p.D746V

c.2237A>T

1 paper

NM_000170.3

p.D746G

c.2237A>G

2 papers

NM_000170.3

p.D746H

c.2236G>C

1 paper

NM_000170.3

p.S748A

c.2242T>G

1 paper

NM_000170.3

p.S748P

c.2242T>C

1 paper

NM_000170.3

p.S748T

c.2242T>A

1 paper

NM_000170.3

p.S745F

c.2234C>T

1 paper

NM_000170.3

p.S745C

c.2234C>G