Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000170.3

p.S564R

c.1690A>C

Surrounding Variants

1 paper

NM_000170.3

p.S564C

c.1690A>T

1 paper

NM_000170.3

p.S564G

c.1690A>G

31 papers

NM_000170.3

p.S564I

c.1691G>T

1 paper

NM_000170.3

p.N563K

c.1689C>G

2 papers

NM_000170.3

p.L562P

c.1685T>C

1 paper

NM_000170.3

p.S566Y

c.1697C>A

1 paper

NM_000170.3

p.M560T

c.1679T>C

3 papers

NM_000170.3

p.M560V

c.1678A>G

1 paper

NM_000170.3

p.T559I

c.1676C>T

2 papers

NM_000170.3

p.T559N

c.1676C>A

7 papers

NM_000170.3

p.A569T

c.1705G>A

1 paper

NM_000170.3

p.C558*

c.1674C>A