Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

18 papers

NM_000170.3

p.A389V

c.1166C>T

Surrounding Variants

1 paper

NM_000170.3

p.A389E

c.1166C>A

1 paper

NM_000170.3

p.A389P

c.1165G>C

1 paper

NM_000170.3

p.L387L

c.1161C>G

1 paper

NM_000170.3

p.M391I

c.1173G>T

1 paper

NM_000170.3

p.M391I

c.1173G>C

1 paper

NM_000170.3

p.M391I

c.1173G>A

1 paper

NM_000170.3

p.A392fs

c.1174_1175fs

1 paper

NM_000170.3

p.A392delFs

c.1175delG

1 paper

NM_000170.3

p.A392_A393del1

c.1176_1178delGCA

1 paper

NM_000170.3

p.M394V

c.1180A>G

1 paper

NM_000170.3

p.M394I

c.1182G>T

1 paper

NM_000170.3

p.M394I

c.1182G>C