Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000170.3

p.M191V

c.571A>G

Surrounding Variants

1 paper

NM_000170.3

p.M191L

c.571A>T

1 paper

NM_000170.3

p.M191L

c.571A>C

1 paper

NM_000170.3

p.M191R

c.572T>G

1 paper

NM_000170.3

p.M191T

c.572T>C

1 paper

NM_000170.3

p.M191K

c.572T>A

1 paper

NM_000170.3

p.D190E

c.570C>G

1 paper

NM_000170.3

p.D190E

c.570C>A

1 paper

NM_000170.3

p.M191I

c.573G>T

1 paper

NM_000170.3

p.M191I

c.573G>C

1 paper

NM_000170.3

p.M191I

c.573G>A

7 papers

NM_000170.3

p.D190V

c.569A>T

1 paper

NM_000170.3

p.D190G

c.569A>G