Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000170.3

p.L189R

c.566T>G

Surrounding Variants

1 paper

NM_000170.3

p.L189P

c.566T>C

1 paper

NM_000170.3

p.L189Q

c.566T>A

1 paper

NM_000170.3

p.L189V

c.565C>G

1 paper

NM_000170.3

p.L189M

c.565C>A

1 paper

NM_000170.3

p.D190Y

c.568G>T

1 paper

NM_000170.3

p.D190H

c.568G>C

1 paper

NM_000170.3

p.D190N

c.568G>A

1 paper

NM_000170.3

p.G188V

c.563G>T

1 paper

NM_000170.3

p.G188A

c.563G>C

1 paper

NM_000170.3

p.G188D

c.563G>A

7 papers

NM_000170.3

p.D190V

c.569A>T

1 paper

NM_000170.3

p.D190G

c.569A>G