Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000170.3

p.C184W

c.552T>G

Surrounding Variants

1 paper

NM_000170.3

p.D185Y

c.553G>T

1 paper

NM_000170.3

p.C184F

c.551G>T

1 paper

NM_000170.3

p.D185H

c.553G>C

1 paper

NM_000170.3

p.C184S

c.551G>C

1 paper

NM_000170.3

p.D185N

c.553G>A

1 paper

NM_000170.3

p.C184Y

c.551G>A

1 paper

NM_000170.3

p.C184G

c.550T>G

1 paper

NM_000170.3

p.C184R

c.550T>C

1 paper

NM_000170.3

p.C184S

c.550T>A

1 paper

NM_000170.3

p.D185V

c.554A>T

1 paper

NM_000170.3

p.D185G

c.554A>G

1 paper

NM_000170.3

p.D185A

c.554A>C