Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000170.3

p.N178K

c.534C>A

Surrounding Variants

1 paper

NM_000170.3

p.N178K

c.534C>G

1 paper

NM_000170.3

p.Y179D

c.535T>G

1 paper

NM_000170.3

p.Y179H

c.535T>C

2 papers

NM_000170.3

p.Y179N

c.535T>A

1 paper

NM_000170.3

p.N178I

c.533A>T

1 paper

NM_000170.3

p.N178S

c.533A>G

1 paper

NM_000170.3

p.N178T

c.533A>C

1 paper

NM_000170.3

p.Y179F

c.536A>T

1 paper

NM_000170.3

p.N178Y

c.532A>T

1 paper

NM_000170.3

p.Y179C

c.536A>G

1 paper

NM_000170.3

p.N178D

c.532A>G

1 paper

NM_000170.3

p.Y179S

c.536A>C