Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000170.3

p.G171E

c.512G>A

Surrounding Variants

1 paper

NM_000170.3

p.G171V

c.512G>T

3 papers

NM_000170.3

p.G171A

c.512G>C

2 papers

NM_000170.3

p.G171W

c.511G>T

1 paper

NM_000170.3

p.G171G

c.513G>C

1 paper

NM_000170.3

p.G171R

c.511G>C

1 paper

NM_000170.3

p.G171R

c.511G>A

1 paper

NM_000170.3

p.Q170H

c.510G>T

1 paper

NM_000170.3

p.Q170H

c.510G>C

1 paper

NM_000170.3

p.R172W

c.514A>T

1 paper

NM_000170.3

p.R172G

c.514A>G

1 paper

NM_000170.3

p.R172M

c.515G>T

1 paper

NM_000170.3

p.R172T

c.515G>C