Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000170.3

p.P166H

c.497C>A

Surrounding Variants

1 paper

NM_000170.3

p.P166L

c.497C>T

1 paper

NM_000170.3

p.P166R

c.497C>G

1 paper

NM_000170.3

p.P166P

c.498T>C

2 papers

NM_000170.3

p.P166S

c.496C>T

1 paper

NM_000170.3

p.P166A

c.496C>G

1 paper

NM_000170.3

p.P166T

c.496C>A

12 papers

NM_000170.3

p.E167*

c.499G>T

1 paper

NM_000170.3

p.Q165H

c.495G>T

1 paper

NM_000170.3

p.E167Q

c.499G>C

1 paper

NM_000170.3

p.Q165H

c.495G>C

1 paper

NM_000170.3

p.E167K

c.499G>A

1 paper

NM_000170.3

p.E167V

c.500A>T