Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000170.3

p.Y164*

c.492C>G

Surrounding Variants

1 paper

NM_000170.3

p.Y164*

c.492C>A

1 paper

NM_000170.3

p.Q165E

c.493C>G

1 paper

NM_000170.3

p.Q165K

c.493C>A

1 paper

NM_000170.3

p.Y164F

c.491A>T

1 paper

NM_000170.3

p.Y164C

c.491A>G

1 paper

NM_000170.3

p.Y164S

c.491A>C

1 paper

NM_000170.3

p.Y164D

c.490T>G

3 papers

NM_000170.3

p.Y164H

c.490T>C

1 paper

NM_000170.3

p.Y164N

c.490T>A

1 paper

NM_000170.3

p.Q165L

c.494A>T

1 paper

NM_000170.3

p.Q165R

c.494A>G

1 paper

NM_000170.3

p.Q165P

c.494A>C