Varaico: Literature-Extracted Genetic Variants

GLDC

361 papers

RefSeq Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H...

Pfam Domains

GDC-Paa 65–488UCSCGlycine cleavage system P-protein

Beta_elim_lyaseaa 585–747UCSCBeta-eliminating lyase

GcvP2_Caa 829–950UCSCGlycine dehydrogenase, C-terminal domain

Gene Aliases

HGNC Name

glycine decarboxylase

HGNC Alias Symbols

GCSP; NKH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000170.3

p.T159I

c.476C>T

Surrounding Variants

1 paper

NM_000170.3

p.T159S

c.476C>G

1 paper

NM_000170.3

p.T159N

c.476C>A

1 paper

NM_000170.3

p.T159S

c.475A>T

1 paper

NM_000170.3

p.T159A

c.475A>G

1 paper

NM_000170.3

p.T159P

c.475A>C

1 paper

NM_000170.3

p.Q160E

c.478C>G

1 paper

NM_000170.3

p.I158M

c.474C>G

1 paper

NM_000170.3

p.Q160K

c.478C>A

1 paper

NM_000170.3

p.I158S

c.473T>G

1 paper

NM_000170.3

p.I158T

c.473T>C

1 paper

NM_000170.3

p.I158N

c.473T>A

1 paper

NM_000170.3

p.Q160L

c.479A>T