Varaico: Literature-Extracted Genetic Variants

Gene:GLP1R
Variant:p.R176K

GLP1R

236 papers

RefSeq Summary

This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions...

Pfam Domains

HRMaa 59–129UCSCHormone receptor domain
7tm_2aa 141–398UCSC7 transmembrane receptor (Secretin family)

Gene Aliases

HGNC Name

glucagon like peptide 1 receptor

HGNC Alias Symbol

GLP-1R

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002062.5
p.R176K
c.527G>A
Surrounding Variants
1 paper
NM_002062.5
p.R176R
c.526A>C
1 paper
NM_002062.5
p.R176G
c.526A>G
2 papers
NM_002062.5
p.R176W
c.526A>T
1 paper
NM_002062.5
p.T175N
c.524C>A
1 paper
NM_002062.5
p.T175I
c.524C>T
2 papers
NM_002062.5
p.H173P
c.518A>C
1 paper
NM_002062.5
p.H173R
c.518A>G
2 papers
NM_002062.5
p.H180Y
c.538C>T
2 papers
NM_002062.5
p.H180R
c.539A>G
1 paper
NM_002062.5
p.H171Q
c.513C>A
1 paper
NM_002062.5
p.H171Q
c.513C>G
1 paper
NM_002062.5
p.H171Y
c.511C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."