Varaico: Literature-Extracted Genetic Variants

Gene:GLP1R
Variant:p.W243R

GLP1R

236 papers

RefSeq Summary

This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions...

Pfam Domains

HRMaa 59–129UCSCHormone receptor domain
7tm_2aa 141–398UCSC7 transmembrane receptor (Secretin family)

Gene Aliases

HGNC Name

glucagon like peptide 1 receptor

HGNC Alias Symbol

GLP-1R

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002062.5
p.W243R
c.727T>A
Surrounding Variants
1 paper
NM_002062.5
p.L244F
c.730C>T
1 paper
NM_002062.5
p.N240S
c.719A>G
2 papers
NM_002062.5
p.A239T
c.715G>A
1 paper
NM_002062.5
p.A238V
c.713C>T
1 paper
NM_002062.5
p.G248D
c.743G>A
2 papers
NM_002062.5
p.V249M
c.745G>A
1 paper
NM_002062.5
p.V249V
c.747G>A
1 paper
NM_002062.5
p.Y250H
c.748T>C
1 paper
NM_002062.5
p.Q234R
c.701A>G
1 paper
NM_002062.5
p.Q234E
c.700C>G
1 paper
NM_002062.5
p.L254M
c.760C>A
1 paper
NM_002062.5
p.L232F
c.694C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."