Varaico: Literature-Extracted Genetic Variants

GLRA2

83 papers

RefSeq Summary

The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encodin...

Pfam Domains

Neur_chan_LBDaa 45–254UCSCNeurotransmitter-gated ion-channel ligand binding domain

Neur_chan_membaa 261–371UCSCNeurotransmitter-gated ion-channel transmembrane region

Gene Aliases

HGNC Name

glycine receptor alpha 2

HGNC Previous Symbol

GLR

Papers

RefSeq ID

Protein change

DNA change

1–12 of 89 variants

10 papers

NM_002063.4

p.N136S

c.407A>G

9 papers

NM_002063.4

p.R153Q

c.458G>A

8 papers

NM_002063.4

p.T296M

c.887C>T

7 papers

NM_002063.4

p.V6L

c.16G>C

7 papers

NM_002063.4

p.R350L

c.1049G>T

6 papers

NM_002063.4

p.V6L

c.16G>T

5 papers

NM_002063.4

p.A288T

c.862G>A

4 papers

NM_002063.4

p.R252C

c.754C>T

3 papers

NM_002063.4

p.M1T

c.2T>C

3 papers

NM_002063.4

p.F47S

c.140T>C

3 papers

NM_002063.4

p.K240E

c.718A>G

3 papers

NM_002063.4

p.I259M

c.777C>G