Varaico: Literature-Extracted Genetic Variants

GLRA2

83 papers

RefSeq Summary

The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encodin...

Pfam Domains

Neur_chan_LBDaa 45–254UCSCNeurotransmitter-gated ion-channel ligand binding domain

Neur_chan_membaa 261–371UCSCNeurotransmitter-gated ion-channel transmembrane region

Gene Aliases

HGNC Name

glycine receptor alpha 2

HGNC Previous Symbol

GLR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_002063.4

p.V6L

c.16G>T

Surrounding Variants

7 papers

NM_002063.4

p.V6L

c.16G>C

1 paper

NM_002063.4

p.I8delFs

c.23delT

3 papers

NM_002063.4

p.M1T

c.2T>C

1 paper

NM_002063.4

p.M1V

c.1A>G

1 paper

NM_002063.4

p.A11D

c.32C>A

1 paper

NM_002063.4

p.N20I

c.59A>T

1 paper

NM_002063.4

p.S34A

c.100T>G

3 papers

NM_002063.4

p.F47S

c.140T>C

1 paper

NM_002063.4

p.D49H

c.145G>C

1 paper

NM_002063.4

p.T55delFs

c.163_164delAC

1 paper

NM_002063.4

p.T55fs

c.163_164fs

1 paper

NM_002063.4

p.G57E

c.170G>A