Varaico: Literature-Extracted Genetic Variants

GLRA2

83 papers

RefSeq Summary

The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encodin...

Pfam Domains

Neur_chan_LBDaa 45–254UCSCNeurotransmitter-gated ion-channel ligand binding domain

Neur_chan_membaa 261–371UCSCNeurotransmitter-gated ion-channel transmembrane region

Gene Aliases

HGNC Name

glycine receptor alpha 2

HGNC Previous Symbol

GLR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002063.4

p.T55delFs

c.163_164delAC

Surrounding Variants

1 paper

NM_002063.4

p.T55fs

c.163_164fs

1 paper

NM_002063.4

p.G57E

c.170G>A

1 paper

NM_002063.4

p.D59N

c.175G>A

1 paper

NM_002063.4

p.D59E

c.177T>A

1 paper

NM_002063.4

p.D49H

c.145G>C

3 papers

NM_002063.4

p.F47S

c.140T>C

1 paper

NM_002063.4

p.N65H

c.193A>C

2 papers

NM_002063.4

p.N65K

c.195T>A

2 papers

NM_002063.4

p.N65K

c.195T>G

1 paper

NM_002063.4

p.S34A

c.100T>G

1 paper

NM_002063.4

p.N20I

c.59A>T

1 paper

NM_002063.4

p.A11D

c.32C>A