Varaico: Literature-Extracted Genetic Variants

GLRA2

83 papers

RefSeq Summary

The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encodin...

Pfam Domains

Neur_chan_LBDaa 45–254UCSCNeurotransmitter-gated ion-channel ligand binding domain

Neur_chan_membaa 261–371UCSCNeurotransmitter-gated ion-channel transmembrane region

Gene Aliases

HGNC Name

glycine receptor alpha 2

HGNC Previous Symbol

GLR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_002063.4

p.K240E

c.718A>G

Surrounding Variants

1 paper

NM_002063.4

p.C243R

c.727T>C

1 paper

NM_002063.4

p.C243W

c.729C>G

1 paper

NM_002063.4

p.I244N

c.731T>A

1 paper

NM_002063.4

p.R252S

c.754C>A

4 papers

NM_002063.4

p.R252C

c.754C>T

2 papers

NM_002063.4

p.R252H

c.755G>A

1 paper

NM_002063.4

p.G255E

c.764G>A

3 papers

NM_002063.4

p.I259M

c.777C>G

1 paper

NM_002063.4

p.L271F

c.813G>C

1 paper

NM_002063.4

p.L271F

c.813G>T

5 papers

NM_002063.4

p.A288T

c.862G>A

8 papers

NM_002063.4

p.T296M

c.887C>T