Varaico: Literature-Extracted Genetic Variants

GLRA2

83 papers

RefSeq Summary

The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encodin...

Pfam Domains

Neur_chan_LBDaa 45–254UCSCNeurotransmitter-gated ion-channel ligand binding domain

Neur_chan_membaa 261–371UCSCNeurotransmitter-gated ion-channel transmembrane region

Gene Aliases

HGNC Name

glycine receptor alpha 2

HGNC Previous Symbol

GLR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002063.4

p.A336T

c.1006G>A

Surrounding Variants

1 paper

NM_002063.4

p.Y335H

c.1003T>C

1 paper

NM_002063.4

p.A337V

c.1010C>T

2 papers

NM_002063.4

p.V341I

c.1021G>A

1 paper

NM_002063.4

p.A322V

c.965C>T

3 papers

NM_002063.4

p.R350C

c.1048C>T

7 papers

NM_002063.4

p.R350L

c.1049G>T

1 paper

NM_002063.4

p.A316P

c.946G>C

1 paper

NM_002063.4

p.V311I

c.931G>A