Varaico: Literature-Extracted Genetic Variants

Gene:GPBAR1
Variant:p.L22Q

GPBAR1

647 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acid...

Pfam Domains

7tm_1aa 31–273UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

G protein-coupled bile acid receptor 1

HGNC Alias Symbols

BG37; GPCR; TGR5; M-BAR; GPCR19; GPR131; MGC40597

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_170699.3
p.L22Q
c.65T>A
Surrounding Variants
1 paper
NM_170699.3
p.L22V
c.64C>G
1 paper
NM_170699.3
p.A23V
c.68C>T
2 papers
NM_170699.3
p.A25T
c.73G>A
1 paper
NM_170699.3
p.G19G
c.57G>C
1 paper
NM_170699.3
p.S26T
c.77G>C
2 papers
NM_170699.3
p.L27V
c.79C>G
1 paper
NM_170699.3
p.L27fs
c.79_80fs
1 paper
NM_170699.3
p.A17P
c.49G>C
1 paper
NM_170699.3
p.I28V
c.82A>G
1 paper
NM_170699.3
p.G16G
c.48G>A
3 papers
NM_170699.3
p.G16R
c.46G>A
2 papers
NM_170699.3
p.G16R
c.46G>C
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