Varaico: Literature-Extracted Genetic Variants

Gene:GPBAR1
Variant:p.L59P

GPBAR1

647 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acid...

Pfam Domains

7tm_1aa 31–273UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

G protein-coupled bile acid receptor 1

HGNC Alias Symbols

BG37; GPCR; TGR5; M-BAR; GPCR19; GPR131; MGC40597

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_170699.3
p.L59P
c.176T>C
Surrounding Variants
1 paper
NM_170699.3
p.L58L
c.174G>C
3 papers
NM_170699.3
p.L57L
c.171A>T
1 paper
NM_170699.3
p.L57Q
c.170T>A
2 papers
NM_170699.3
p.L57P
c.170T>C
1 paper
NM_170699.3
p.G61G
c.183G>A
1 paper
NM_170699.3
p.L62M
c.184C>A
3 papers
NM_170699.3
p.L55Q
c.164T>A
1 paper
NM_170699.3
p.L63H
c.188T>A
2 papers
NM_170699.3
p.T64S
c.190A>T
1 paper
NM_170699.3
p.F53Y
c.158T>A
1 paper
NM_170699.3
p.F53I
c.157T>A
1 paper
NM_170699.3
p.L66L
c.198G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."