Varaico: Literature-Extracted Genetic Variants

Gene:GPBAR1
Variant:p.L141R

GPBAR1

647 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acid...

Pfam Domains

7tm_1aa 31–273UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

G protein-coupled bile acid receptor 1

HGNC Alias Symbols

BG37; GPCR; TGR5; M-BAR; GPCR19; GPR131; MGC40597

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_170699.3
p.L141R
c.422T>G
Surrounding Variants
1 paper
NM_170699.3
p.P142A
c.424C>G
1 paper
NM_170699.3
p.A143T
c.427G>A
1 paper
NM_170699.3
p.A143S
c.427G>T
1 paper
NM_170699.3
p.F138Y
c.413T>A
1 paper
NM_170699.3
p.W146*
c.437G>A
1 paper
NM_170699.3
p.L136M
c.406C>A
1 paper
NM_170699.3
p.H148Q
c.444C>A
1 paper
NM_170699.3
p.H148Q
c.444C>G
2 papers
NM_170699.3
p.T150A
c.448A>G
2 papers
NM_170699.3
p.T150I
c.449C>T
1 paper
NM_170699.3
p.W132S
c.395G>C
1 paper
NM_170699.3
p.W132L
c.395G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."