Varaico: Literature-Extracted Genetic Variants

GPS1

33 papers

RefSeq Summary

This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of ...

Pfam Domains

RPN7aa 107–289UCSC26S proteasome subunit RPN7

PCIaa 320–408UCSCPCI domain

CSN1_Caa 411–438UCSCCOP9 signalosome complex subunit 1, C-terminal helix

Gene Aliases

HGNC Name

G protein pathway suppressor 1

HGNC Alias Symbols

COPS1; CSN1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001321092.3

p.T143T

c.429A>G

Surrounding Variants

1 paper

NM_001321092.3

p.A134V

c.401C>T

1 paper

NM_001321092.3

p.V194I

c.580G>A

1 paper

NM_001321092.3

p.R96H

c.287G>A

2 papers

NM_001321092.3

p.V88M

c.262G>A

1 paper

NM_001321092.3

p.V82M

c.244G>A

1 paper

NM_001321092.3

p.V72M

c.214G>A

1 paper

NM_001321092.3

p.A48T

c.142G>A

1 paper

NM_001321092.3

p.A13T

c.37G>A

1 paper

NM_001321092.3

p.I307V

c.919A>G

1 paper

NM_001321092.3

p.A395A

c.1185C>T

1 paper

NM_001321092.3

p.L400fs

c.1198_1199fs

1 paper

NM_001321092.3

p.T401insFs

c.1201dupA